Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417442 | 0.78 | MTNR1A (0.41) | MTNR1AMTNR1BEIF4A3VCPTSHR | |
| SCHEMBL7420510 | 0.74 | KMT2A (0.53) | MTNR1AMTNR1BKDM4EHSD17B10HPGD | |
| SCHEMBL7418770 | 0.72 | MTNR1A (0.47) | MTNR1AMTNR1BVCPKDM4EHSD17B10 | |
| SCHEMBL31397049 | 0.71 | TAS1R3 (0.48) | ALOX15MAPT | |
| SCHEMBL5981755 | 0.69 | CASP3 (0.51) | MTNR1AMTNR1BKDM4EHSD17B10KDM5A | |
| SCHEMBL7469548 | 0.68 | KDM4E (0.42) | MTNR1AMTNR1BKDM4EHSD17B10TSHR | |
| SCHEMBL6797382 | 0.68 | POLB (0.47) | HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL7423385 | 0.68 | MTNR1A (0.43) | MTNR1AMTNR1BVCPKDM4EHSD17B10 | |
| SCHEMBL7418610 | 0.67 | PPARG (0.48) | MTNR1AMTNR1BKDM4EHSD17B10TSHR | |
| SCHEMBL7411302 | 0.67 | L3MBTL1 (0.48) | MTNR1AMTNR1BKDM4EHSD17B10KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |