Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316694 | 0.88 | MEN1 (0.50) | LNPEPKMT2AMEN1ITGB1ITGA4 | |
| SCHEMBL7428016 | 0.82 | ITGA4 (0.58) | LNPEPITGB1ITGA4ATM | |
| Hydrochloric Acid SCHEMBL6510331 | 0.81 | ITGA4 (0.57) | LNPEPITGB1ITGA4ATM | |
| SCHEMBL7432829 | 0.77 | ITGB1 (0.44) | ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL27577165 | 0.76 | KMT2A (0.51) | LNPEPKMT2AMEN1ITGB1ITGA4 | |
| Hydrochloric Acid SCHEMBL6108925 | 0.76 | ITGA4 (0.50) | KMT2AMEN1ITGB1ITGA4L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6738903 | 0.76 | KMT2A (0.51) | LNPEPKMT2AMEN1ITGB1ITGA4 | |
| SCHEMBL13398330 | 0.74 | LNPEP (0.48) | LNPEPKMT2AATMNOS2NOS3 | |
| SCHEMBL13628884 | 0.74 | LNPEP (0.48) | LNPEPKMT2AATMNOS2NOS3 | |
| SCHEMBL7896689 | 0.73 | NOS2 (0.48) | LNPEPKMT2AMEN1NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035127-A1 | Phenylalanine derivatives | CELLTECH THERAPEUTIS, LIMITED | 2002-03-21 | — | — | US | disclosed |
| US-6329372-B1 | HETEROCYCLIC AMIDE COMPOUNDS ARE ABLE TO INHIBIT THE BINDING OF ALPHA4 INTEGRINS TO THEIR LIGANDS AND ARE OF USE IN THE PROPHYLAXIS AND TREATMENT OF IMMUNE OR INFLAMMATORY DISORDERS. | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |
| EP-1051399-A1 | PHENYLALANINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037618-A1 | PHENYLALANINE DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035127-A1 | Phenylalanine derivatives | PAH, VCAM1, IL4I1 | LNPEP 848/4885KMT2A 2045/4885MEN1 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.