Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421892 | 0.86 | NR4A2 (0.51) | NR4A2MAOBLTB4RLTB4R2ALOX5 | |
| SCHEMBL7424530 | 0.86 | LTB4R (0.44) | NR4A2MAOBLTB4RLTB4R2ALOX5 | |
| SCHEMBL7424454 | 0.86 | NR4A2 (0.49) | NR4A2MAOBLTB4RLTB4R2ALOX5 | |
| SCHEMBL7420337 | 0.83 | FAAH (0.42) | LTB4RLTB4R2ALOX5PTGESCYSLTR2 | |
| SCHEMBL6834465 | 0.83 | LTB4R (0.45) | MAOBLTB4RLTB4R2ALOX5PTGES | |
| SCHEMBL7428935 | 0.82 | KEAP1 (0.41) | NR4A2LTB4RLTB4R2ALOX5FFAR4 | |
| SCHEMBL7427123 | 0.82 | LTB4R (0.44) | NR4A2MAOBLTB4RLTB4R2ALOX5 | |
| SCHEMBL7426641 | 0.82 | LTB4R (0.47) | NPC1LTB4RLTB4R2ALOX5PTGES | |
| SCHEMBL7427483 | 0.78 | SLC1A5 (0.54) | MAOBFFAR1FFAR4 | |
| SCHEMBL7378945 | 0.77 | MEN1 (0.48) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |