Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424454 | 0.88 | NR4A2 (0.49) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7426589 | 0.87 | MAOB (0.51) | LTB4RLTB4R2ALOX5NPC1HTT | |
| SCHEMBL7421865 | 0.87 | MAOB (0.51) | LTB4RLTB4R2ALOX5NPC1HTT | |
| SCHEMBL6834465 | 0.87 | LTB4R (0.45) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7424530 | 0.86 | LTB4R (0.44) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7427123 | 0.86 | LTB4R (0.44) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7421892 | 0.86 | NR4A2 (0.51) | LTB4RLTB4R2ALOX5 | |
| SCHEMBL7420337 | 0.85 | FAAH (0.42) | LTB4RLTB4R2ALOX5PTGESCYP2D6 | |
| SCHEMBL7424281 | 0.82 | NR4A2 (0.49) | LTB4RLTB4R2GPR132ALOX5PTGES | |
| SCHEMBL7421351 | 0.80 | MMP13 (0.48) | LTB4RLTB4R2GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |