Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426448 | 0.88 | GRN (0.44) | SMN1; SMN2MAPTKDM4EHTTALDH1A1 | |
| SCHEMBL7426239 | 0.88 | MEN1 (0.43) | SMN1; SMN2MAPTKDM4EHTTALDH1A1 | |
| SCHEMBL7425602 | 0.86 | ROCK1 (0.41) | KMT2AMEN1FNTAFNTBPGGT1B | |
| SCHEMBL7423334 | 0.84 | DHFR (0.34) | MAPTALDH1A1TAS1R3TAS1R1CYP2C19 | |
| SCHEMBL7426736 | 0.81 | CTSK (0.48) | SMN1; SMN2MAPTKDM4EHTTALDH1A1 | |
| SCHEMBL7417292 | 0.78 | ALDH1A1 (0.34) | MAPTKDM4EALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL5869832 | 0.76 | ACE2 (0.38) | SMN1; SMN2MAPTKDM4EHTTALDH1A1 | |
| SCHEMBL7426920 | 0.75 | CTSK (0.38) | MAPTKDM4EALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL7417825 | 0.74 | GRN (0.43) | MAPTHTTALDH1A1MAPK1GRN | |
| SCHEMBL7382345 | 0.74 | CTSK (0.41) | SMN1; SMN2MAPTHTTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |