Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535719 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2F2RL1FFAR1ALDH1A1MEN1 | |
| SCHEMBL1236959 | 0.73 | CALM1 (0.53) | SMN1; SMN2F2RL1FFAR1ALDH1A1POLB | |
| SCHEMBL18065719 | 0.73 | NPC1 (0.58) | F2RL1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL1237071 | 0.72 | ALOX5 (0.49) | F2RL1ALDH1A1 | |
| SCHEMBL10644144 | 0.72 | PPARA (0.50) | SMN1; SMN2F2RL1FFAR1LDHA | |
| SCHEMBL10778646 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2F2RL1ALDH1A1POLBHTT | |
| SCHEMBL8939115 | 0.71 | TAAR1 (0.53) | SMN1; SMN2F2RL1TAAR1 | |
| SCHEMBL16341200 | 0.71 | ACACB (0.60) | SMN1; SMN2F2RL1MEN1KMT2AHTT | |
| SCHEMBL25596188 | 0.71 | F2RL1 (0.47) | SMN1; SMN2F2RL1FFAR1LDHA | |
| SCHEMBL18065675 | 0.71 | MEN1 (0.56) | F2RL1ALDH1A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |