Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244844 | 0.82 | CCR1 (0.49) | SMN1; SMN2OPRD1OPRK1CHRM4DRD2 | |
| SCHEMBL23112637 | 0.82 | LMNA (0.43) | SMN1; SMN2OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL3045886 | 0.81 | CNR1 (0.49) | SMN1; SMN2DRD2DRD3DRD4S1PR2 | |
| SCHEMBL17009523 | 0.80 | KMT2A (0.46) | SMN1; SMN2OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7478597 | 0.79 | MEN1 (0.48) | SMN1; SMN2OPRD1OPRK1CHRM4DRD2 | |
| SCHEMBL19212251 | 0.77 | OPRD1 (0.43) | SMN1; SMN2OPRD1OPRK1CHRM4HRH1 | |
| SCHEMBL7422101 | 0.77 | CHRM4 (0.45) | SMN1; SMN2OPRD1OPRK1CHRM4HRH1 | |
| SCHEMBL7485189 | 0.76 | CCR1 (0.45) | OPRD1OPRK1DRD2DRD3HRH1 | |
| SCHEMBL8696969 | 0.75 | RORC (0.58) | SMN1; SMN2OPRD1OPRK1CHRM4DRD2 | |
| SCHEMBL7511921 | 0.74 | POLB (0.52) | SMN1; SMN2CHRM4LMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |