Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432535 | 0.99 | HSD11B1 (0.45) | KMT2ATP53LMNAMEN1ALDH1A1 | |
| SCHEMBL7442890 | 0.86 | ACE (0.40) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7432468 | 0.80 | HSD11B1 (0.46) | KMT2AMEN1HSD11B1SMN1; SMN2HTT | |
| SCHEMBL7425886 | 0.79 | HSD11B1 (0.44) | KMT2ATP53LMNAMEN1ALDH1A1 | |
| SCHEMBL7432526 | 0.78 | HSD11B1 (0.46) | KMT2ATP53LMNAMEN1ALDH1A1 | |
| SCHEMBL7432645 | 0.76 | ENPP2 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7436715 | 0.75 | SIGMAR1 (0.37) | KMT2AMEN1SMN1; SMN2HTTPOLB | |
| SCHEMBL7434183 | 0.75 | ALDH1A1 (0.37) | KMT2ALMNAMEN1ALDH1A1HSD11B1 | |
| SCHEMBL7426794 | 0.74 | POLB (0.37) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL7445427 | 0.74 | ALDH1A1 (0.41) | KMT2ALMNAMEN1ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7126258-A | — | — | None | — | — | JP | disclosed |
| JP-H07126258-A | HYDANTOIN DERIVATIVE | FUJIREBIO INC | 1995-05-16 | — | — | JP | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |