Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 4/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444733 | 0.88 | ALDH1A1 (0.40) | SIGMAR1L3MBTL1POLBGAAMEN1 | |
| SCHEMBL7436708 | 0.78 | L3MBTL1 (0.39) | L3MBTL1GAAMEN1MAPTKMT2A | |
| SCHEMBL7432535 | 0.77 | HSD11B1 (0.45) | MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7432645 | 0.76 | ENPP2 (0.47) | L3MBTL1POLBGAAMEN1USP2 | |
| SCHEMBL7425893 | 0.75 | KMT2A (0.44) | POLBMEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7426794 | 0.74 | POLB (0.37) | L3MBTL1POLBSLC6A3GAAMEN1 | |
| SCHEMBL7440468 | 0.74 | POLB (0.37) | L3MBTL1POLBGAAMEN1USP2 | |
| SCHEMBL7428792 | 0.73 | CYP2D6 (0.45) | POLBKMT2AACE | |
| SCHEMBL7432509 | 0.73 | TSHR (0.33) | L3MBTL1POLBGAAMEN1USP2 | |
| SCHEMBL7445702 | 0.72 | ACHE (0.40) | MCHR1L3MBTL1POLBSLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |