Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425893 | 0.86 | KMT2A (0.44) | POLBHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7432535 | 0.85 | HSD11B1 (0.45) | HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7432468 | 0.79 | HSD11B1 (0.46) | HSD17B2POLBGAAHTTMAPK1 | |
| SCHEMBL7442881 | 0.78 | ADORA2A (0.38) | ACEADORA2ASIGMAR1MMESMN1; SMN2 | |
| SCHEMBL7432645 | 0.76 | ENPP2 (0.47) | POLBGAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL7426794 | 0.73 | POLB (0.37) | HSD17B2POLBGAAHTTMAPK1 | |
| SCHEMBL7428792 | 0.72 | CYP2D6 (0.45) | ACEMMEPOLBKMT2A | |
| SCHEMBL7436715 | 0.72 | SIGMAR1 (0.37) | ACESIGMAR1POLBGAAHTT | |
| SCHEMBL7445702 | 0.72 | ACHE (0.40) | HSD17B2POLBGAAHTTSMN1; SMN2 | |
| SCHEMBL7435831 | 0.72 | ACHE (0.40) | ACEHSD17B2POLBGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |