Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396119 | 0.90 | MMP3 (0.44) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7366460 | 0.85 | MMP3 (0.42) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7361335 | 0.83 | MMP3 (0.42) | MMP3MMP1MMP2CTSDMMP9 | |
| SCHEMBL7356789 | 0.82 | MMP3 (0.43) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7358533 | 0.80 | MMP3 (0.39) | MMP3MMP1MMP2CTSDMMP9 | |
| SCHEMBL7368214 | 0.79 | LNPEP (0.41) | MMP3MMP1MMP2PSMB5 | |
| SCHEMBL7423322 | 0.79 | ERAP2 (0.40) | MMP3MMP1MMP2CTSDMMP9 | |
| SCHEMBL7355861 | 0.78 | PSMB1 (0.41) | MMP3MMP1PSMB5 | |
| SCHEMBL7364939 | 0.77 | ERAP2 (0.40) | MMP3MMP1MMP2 | |
| SCHEMBL7400006 | 0.76 | MMP3 (0.42) | MMP3MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |