Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.42 |
| ▸ | MMP1 | P03956 | 10/20 | 0.41 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356789 | 0.89 | MMP3 (0.43) | MMP3MMP1MMP2PRCPMMP9 | |
| SCHEMBL7396119 | 0.87 | MMP3 (0.44) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7425968 | 0.85 | MMP3 (0.40) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7361335 | 0.83 | MMP3 (0.42) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7357789 | 0.83 | CA12 (0.40) | MMP3MMP1MMP2 | |
| SCHEMBL7423322 | 0.81 | ERAP2 (0.40) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7358533 | 0.81 | MMP3 (0.39) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7355861 | 0.80 | PSMB1 (0.41) | MMP3MMP1 | |
| SCHEMBL7368214 | 0.79 | LNPEP (0.41) | MMP3MMP1MMP2 | |
| SCHEMBL7364939 | 0.79 | ERAP2 (0.40) | MMP3MMP1MMP2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0845002-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040745-A2 | AMINO ACID AMIDES OF 5-AMINO-1,3,4-THIADIAZONES AND THEIR USE AS INHIBITORS FOR MATRIX METALLOPROTEINASES | PROSCRIPT, INC. (US) | 1996-12-19 | — | — | WO | disclosed |