Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306308 | 0.79 | EPHX2 (0.37) | MAPK1 | |
| SCHEMBL6716719 | 0.79 | EPHX2 (0.37) | MAPK1 | |
| SCHEMBL6071126 | 0.76 | GAA (0.40) | TDP1KMT2A | |
| SCHEMBL27265721 | 0.74 | L3MBTL1 (0.40) | L3MBTL1TSHRTDP1PPARGMAPK1 | |
| SCHEMBL7737636 | 0.72 | SIGMAR1 (0.37) | — | |
| SCHEMBL27267425 | 0.71 | L3MBTL1 (0.40) | L3MBTL1TSHRTDP1MAPK1KDM4E | |
| SCHEMBL7483092 | 0.69 | ALDH1A1 (0.40) | L3MBTL1TSHRPPARGMAPK1KDM4E | |
| SCHEMBL27492109 | 0.69 | GAA (0.54) | L3MBTL1TSHRTDP1PPARGMAPK1 | |
| SCHEMBL3809340 | 0.68 | NR1D1 (0.52) | MAPK1KDM4EALDH1A1ATM | |
| SCHEMBL7346477 | 0.68 | KDM1A (0.38) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036596-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |