Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429170 | 0.92 | ALDH1A1 (0.46) | ALDH1A1CACNA1BEGLN2EGLN1SCN9A | |
| SCHEMBL7423140 | 0.90 | CTSS (0.48) | ALDH1A1EGLN2EGLN1CTSLCTSS | |
| SCHEMBL7425607 | 0.89 | CTSL (0.48) | CACNA1BCTSLCTSSCTSKCTSB | |
| SCHEMBL7428201 | 0.85 | GRN (0.46) | ALDH1A1EGLN2CTSLCTSSCTSK | |
| SCHEMBL7417901 | 0.80 | FOLH1 (0.57) | ALDH1A1CTSSCTSKFPR2MAPT | |
| SCHEMBL7378949 | 0.80 | MME (0.50) | ALDH1A1CTSSCTSK | |
| SCHEMBL7422327 | 0.79 | GAA (0.47) | MAPT | |
| SCHEMBL7425053 | 0.78 | CA2 (0.50) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL7424801 | 0.77 | CTSS (0.46) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL7427045 | 0.76 | GRIA2 (0.52) | ALDH1A1CTSLFPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |