Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426514 | 0.92 | ALDH1A1 (0.46) | ALDH1A1CTSLCTSSCTSKEGLN2 | |
| SCHEMBL7423140 | 0.87 | CTSS (0.48) | ALDH1A1CTSLCTSSCTSKEGLN2 | |
| SCHEMBL7428201 | 0.86 | GRN (0.46) | ALDH1A1CTSLCTSSCTSKEGLN2 | |
| SCHEMBL7425607 | 0.81 | CTSL (0.48) | CTSLCTSSCTSKCACNA1BFOLH1 | |
| SCHEMBL7426474 | 0.80 | GRIA2 (0.52) | ALDH1A1CTSLMAPTFPR2 | |
| SCHEMBL7427045 | 0.80 | GRIA2 (0.52) | ALDH1A1CTSLMAPTFPR2 | |
| SCHEMBL7421300 | 0.78 | RAB9A (0.40) | ALDH1A1CTSLCTSSCTSKEGLN1 | |
| SCHEMBL7417901 | 0.78 | FOLH1 (0.57) | ALDH1A1CTSSCTSKMAPTFPR2 | |
| SCHEMBL7378949 | 0.77 | MME (0.50) | ALDH1A1CTSSCTSKFOLH1GAA | |
| SCHEMBL8249538 | 0.77 | ALDH1A1 (0.47) | ALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |