Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440239 | 0.80 | PNMT (0.39) | THRBHPGDKMT2A | |
| SCHEMBL7426673 | 0.78 | HPGD (0.48) | TRPV1HDAC1HDAC3HDAC2HDAC6 | |
| SCHEMBL7434823 | 0.78 | AR (0.37) | THRBHPGD | |
| SCHEMBL7446269 | 0.76 | HPGD (0.32) | HPGD | |
| SCHEMBL7437340 | 0.75 | CA2 (0.42) | KMT2A | |
| SCHEMBL29604675 | 0.73 | TAAR1 (0.62) | TRPV1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL18414428 | 0.73 | TRPV1 (0.52) | TRPV1CALM1TAAR1SKP2HPGD | |
| SCHEMBL4055725 | 0.73 | TAAR1 (0.62) | TRPV1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL2487394 | 0.72 | CA2 (0.48) | — | |
| SCHEMBL7430118 | 0.72 | TAAR1 (0.40) | TRPV1CALM1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |