Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427958 | 0.80 | TSHR (0.47) | HPGDMAPTKMT2ATSHRTHRA | |
| SCHEMBL7440246 | 0.80 | HPGD (0.44) | HPGDALDH1A1KMT2ATHRBMEN1 | |
| SCHEMBL7426663 | 0.78 | TRPV1 (0.38) | HPGDKMT2ATHRATHRBTRPV1 | |
| SCHEMBL7434827 | 0.78 | HPGD (0.45) | HPGDALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL9412081 | 0.76 | HPGD (0.50) | HPGDALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL7446273 | 0.76 | HPGD (0.44) | HPGDALDH1A1MAPTKMT2ATSHR | |
| SCHEMBL7437345 | 0.75 | RAB9A (0.50) | HPGDALDH1A1MAPTRAB9A | |
| SCHEMBL7430118 | 0.74 | TAAR1 (0.40) | HPGDKMT2ATRPV1HDAC1HDAC3 | |
| SCHEMBL1292040 | 0.74 | ALDH1A1 (0.46) | HPGDALDH1A1THRATHRBTRPV1 | |
| SCHEMBL9255724 | 0.73 | CYP4F2 (0.54) | HPGDALDH1A1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |