Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434827 | 0.80 | HPGD (0.45) | HSD17B10ALDH1A1HPGDKDM4ETHRB | |
| SCHEMBL7434681 | 0.80 | HCRTR2 (0.36) | HSD17B10ALDH1A1KDM4EMAOBNPC1 | |
| SCHEMBL7426663 | 0.78 | TRPV1 (0.38) | HPGDTHRB | |
| SCHEMBL7440239 | 0.74 | PNMT (0.39) | HSD17B10ALDH1A1HPGDKDM4ETHRB | |
| SCHEMBL7437379 | 0.74 | MAOA (0.35) | ARHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL7446269 | 0.73 | HPGD (0.32) | HPGD | |
| SCHEMBL7437340 | 0.72 | CA2 (0.42) | MAOBNPC1RAB9A | |
| SCHEMBL14501846 | 0.72 | LMNA (0.44) | ARHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL14501849 | 0.72 | LMNA (0.44) | ARHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL7443159 | 0.69 | CA2 (0.48) | MAOBNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |