Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440246 | 0.81 | HPGD (0.44) | PNMTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL7435505 | 0.76 | PNMT (0.36) | PNMTHTR6CHRM2POLBALDH1A1 | |
| SCHEMBL7446269 | 0.75 | HPGD (0.32) | HPGD | |
| SCHEMBL7437340 | 0.71 | CA2 (0.42) | KMT2ACA2 | |
| SCHEMBL7435716 | 0.69 | PNMT (0.33) | PNMTCHRM2POLBALDH1A1KDM4E | |
| SCHEMBL7436261 | 0.69 | ALDH1A1 (0.32) | ALDH1A1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL7443159 | 0.68 | CA2 (0.48) | HTTCA2 | |
| SCHEMBL2487394 | 0.68 | CA2 (0.48) | HTTCA2 | |
| SCHEMBL7445863 | 0.68 | MTNR1A (0.44) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1299584 | 0.66 | NISCH (0.44) | POLBALDH1A1HTTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |