Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436245 | 0.85 | THRB (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL7285870 | 0.82 | PHF8 (0.52) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL10701326 | 0.82 | PAM (0.46) | EGLN1PAMALDH1A1KMT2AMAPT | |
| SCHEMBL7429768 | 0.80 | GAA (0.48) | EGLN1ALDH1A1CYP1A2L3MBTL1KMT2A | |
| SCHEMBL22915367 | 0.80 | ALDH1A1 (0.41) | PHF8KDM2AEGLN1KDM6BKDM5C | |
| SCHEMBL25179494 | 0.76 | CYP2D6 (0.33) | PHF8KDM2AEGLN1CYP2D6LTA4H | |
| SCHEMBL7433528 | 0.74 | TSHR (0.58) | EGLN1ALDH1A1KMT2AMAPTTSHR | |
| SCHEMBL25183111 | 0.73 | ALDH1A1 (0.48) | PHF8KDM2AKDM5CALDH1A1KDM7A | |
| SCHEMBL7433877 | 0.72 | POLB (0.43) | ALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL31369528 | 0.72 | ALDH1A1 (0.47) | PHF8KDM2AALDH1A1KDM7AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |