Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429240 | 0.85 | PHF8 (0.35) | L3MBTL1ALDH1A1 | |
| SCHEMBL7432168 | 0.82 | EPHX2 (0.54) | THRBATML3MBTL1LMNAEPHX2 | |
| SCHEMBL7429754 | 0.73 | — | — | |
| SCHEMBL7285870 | 0.70 | PHF8 (0.52) | L3MBTL1LMNAALDH1A1 | |
| SCHEMBL10701326 | 0.70 | PAM (0.46) | THRBLMNAALDH1A1 | |
| SCHEMBL7434725 | 0.70 | LMNA (0.50) | ATMLMNAEPHX1POLB | |
| SCHEMBL7429768 | 0.69 | GAA (0.48) | L3MBTL1ALDH1A1 | |
| SCHEMBL7440996 | 0.68 | NAAA (0.49) | THRBL3MBTL1LMNAEPHX2ALDH1A1 | |
| SCHEMBL22915367 | 0.68 | ALDH1A1 (0.41) | ALDH1A1 | |
| Succinic Acid SCHEMBL28239934 | 0.68 | ALDH1A1 (0.67) | THRBATML3MBTL1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |