Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432442 | 0.99 | L3MBTL1 (0.44) | KMT2AALDH1A1HPGDGAAPOLB | |
| SCHEMBL7427426 | 0.86 | LTB4R (0.39) | KMT2AMEN1MAPT | |
| SCHEMBL7440894 | 0.85 | KMT2A (0.48) | KMT2AALDH1A1HPGDGAAPOLB | |
| SCHEMBL7433775 | 0.84 | KMT2A (0.47) | KMT2AALDH1A1HPGDGAAPOLB | |
| SCHEMBL7431831 | 0.83 | KDM4E (0.60) | KMT2AALDH1A1HPGDGAAPOLB | |
| SCHEMBL7442252 | 0.83 | SELP (0.47) | KMT2AGAALMNAMEN1MAPK1 | |
| SCHEMBL7430649 | 0.83 | SELL (0.56) | KMT2AALDH1A1GAAL3MBTL1LMNA | |
| SCHEMBL7430609 | 0.82 | NPC1 (0.46) | KMT2AALDH1A1POLBMEN1MAPT | |
| SCHEMBL7429346 | 0.81 | SELL (0.45) | KMT2AALDH1A1GAAPOLBL3MBTL1 | |
| SCHEMBL7433940 | 0.80 | LTB4R (0.62) | KMT2AHPGDPOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |