Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430649 | 0.86 | SELL (0.56) | LTB4RSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL7442252 | 0.86 | SELP (0.47) | LTB4RHDAC1KMT2AMEN1AKR1C3 | |
| SCHEMBL7430609 | 0.85 | NPC1 (0.46) | LTB4RSMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL7434116 | 0.85 | LTB4R (0.67) | LTB4RSMN1; SMN2POLBHDAC1HDAC8 | |
| SCHEMBL7429346 | 0.84 | SELL (0.45) | LTB4RPOLBKMT2AMEN1MAPT | |
| SCHEMBL7439374 | 0.80 | KMT2A (0.44) | POLBKMT2AMEN1MAPTHPGD | |
| SCHEMBL7435487 | 0.80 | HDAC3 (0.49) | SMN1; SMN2POLBHDAC1HDAC8HDAC6 | |
| SCHEMBL7432442 | 0.79 | L3MBTL1 (0.44) | POLBKMT2AMEN1MAPTHPGD | |
| SCHEMBL7427426 | 0.79 | LTB4R (0.39) | LTB4RKMT2AMEN1MAPTAKR1C3 | |
| SCHEMBL7432797 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |