Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 11/20 | 0.39 |
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424732 | 0.88 | MAPK1 (0.39) | MAPK1FFAR1MMEACEDCLRE1B | |
| SCHEMBL7422595 | 0.82 | RXRA (0.40) | MAPK1MMEACEPTGES | |
| SCHEMBL7425621 | 0.81 | SOS1 (0.44) | MAPK1TYMP | |
| SCHEMBL7424958 | 0.79 | APP (0.39) | MAPK1CNR2 | |
| SCHEMBL7419980 | 0.79 | AOC3 (0.46) | MAPK1TAAR1 | |
| SCHEMBL7419478 | 0.78 | MMP2 (0.42) | MMEACECNR2 | |
| SCHEMBL7424891 | 0.76 | PTGS2 (0.43) | FFAR1PTGES | |
| SCHEMBL7426730 | 0.76 | AOC3 (0.43) | MAPK1TAAR1 | |
| SCHEMBL7427483 | 0.76 | SLC1A5 (0.54) | FFAR1 | |
| SCHEMBL7421892 | 0.74 | NR4A2 (0.51) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |