Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426076 | 0.89 | LTA4H (0.49) | ALDH1A1KDM4EMEN1KMT2AKCNJ1 | |
| SCHEMBL24168843 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EFFAR1MEN1KMT2A | |
| SCHEMBL3128583 | 0.84 | HSPB1 (0.59) | ALDH1A1KDM4EMEN1KMT2AHSPB1 | |
| SCHEMBL7632953 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4EFFAR1MEN1KMT2A | |
| SCHEMBL27188054 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4EFFAR1MEN1KMT2A | |
| SCHEMBL10923033 | 0.83 | PDE4A (0.55) | ALDH1A1MEN1KMT2APGRMAPT | |
| SCHEMBL7075419 | 0.82 | VCAM1 (0.50) | ALDH1A1KDM4EMEN1KMT2AVCAM1 | |
| SCHEMBL6578552 | 0.81 | MERTK (0.53) | ALDH1A1KDM4EMEN1KMT2AVCAM1 | |
| SCHEMBL2749527 | 0.81 | MEN1 (0.58) | ALDH1A1KDM4EMEN1KMT2AVCAM1 | |
| SCHEMBL9214229 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4EFFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1948964-A | Synthesizing porcess for artificial antigen of cyanobromide chrysanthemum ester and assaying process thereof | ZHAO JIANZHUANG (CN) | 2007-04-18 | — | — | CN | claimed |
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |
| CN-103619818-A | Heterocyclic compounds for treating helminth infections | DU PONT | 2014-03-05 | — | — | CN | disclosed |
| US-20140045833-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| US-20140045833-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| WO-2012135944-A9 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2014-01-09 | — | — | WO | disclosed |
| US-8268885-B2 | Entry inhibitors of the HIV virus | JANSSEN R&D IRELAND (IE) | 2012-09-18 | — | — | US | disclosed |
| EP-1667675-B1 | ENTRY INHIBITORS OF THE HIV VIRUS | TIBOTEC PHARM LTD (IE) | 2011-11-09 | — | — | EP | disclosed |
| CN-1948964-A | Synthesizing porcess for artificial antigen of cyanobromide chrysanthemum ester and assaying process thereof | ZHAO JIANZHUANG (CN) | 2007-04-18 | — | — | CN | disclosed |
| US-20070066623-A1 | Entry inhibitors of the hiv virus | JANSSEN R&D IRELAND (IE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066623-A1 | Entry inhibitors of the hiv virus | JANSSEN R&D IRELAND (IE) | 2007-03-22 | — | — | US | disclosed |
| CN-1315942-A | 2-oxo-j(2H)-quinoline derivatives | MERCK PATENT GMBH (DE) | 2001-10-03 | — | — | CN | disclosed |
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066623-A1 | Entry inhibitors of the hiv virus | HAVCR2, CCR5, SAMHD1 | ALDH1A1 3208/4885KDM4E 2453/4885FFAR1 4388/4885 |
| US-20140045833-A1 | Protein Kinase Inhibitors | LCK, BTK, TEC | ALDH1A1 4846/4885KDM4E 1287/4885FFAR1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.