Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683061 | 0.92 | PYGL (0.43) | PYGLCYP2C9MMP1MMP7ACE | |
| SCHEMBL7421589 | 0.83 | PYGL (0.43) | PYGLCYP2C9MMP1MMP7ACE | |
| SCHEMBL7428036 | 0.83 | CA2 (0.45) | PYGLCYP2C9MMP1MMP7ACE | |
| SCHEMBL7703492 | 0.79 | CA2 (0.42) | ACECCKBRCA2 | |
| SCHEMBL7425669 | 0.75 | ALDH1A1 (0.52) | MMP1MMP7ACEMMP12MMP13 | |
| SCHEMBL7684139 | 0.74 | CA2 (0.48) | MMP1MMP7ACEMMP12MMP13 | |
| SCHEMBL7659998 | 0.71 | MEN1 (0.45) | PYGLCYP2C9CCKBRCASP1 | |
| SCHEMBL7702126 | 0.71 | PLAT (0.45) | CCKBRCA2CASP1 | |
| SCHEMBL7668106 | 0.71 | CASP1 (0.46) | PYGLCYP2C9CCKBRCASP1 | |
| SCHEMBL7422050 | 0.71 | KCNA5 (0.49) | MMP1MMP7ACEMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |