Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424089 | 0.90 | LMNA (0.52) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL4159802 | 0.81 | MMP2 (0.49) | L3MBTL1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7429208 | 0.77 | L3MBTL1 (0.52) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL19578472 | 0.76 | L3MBTL1 (0.49) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL5256532 | 0.75 | L3MBTL1 (0.52) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL205765 | 0.74 | MGLL (0.65) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.74 | LMNA (0.73) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL160429 | 0.73 | KCNA5 (0.67) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL10243339 | 0.73 | LMNA (0.71) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL9551351 | 0.73 | L3MBTL1 (0.49) | L3MBTL1MAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |