Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434317 | 0.90 | POLB (0.46) | LMNANPSR1ATMGAAHTT | |
| SCHEMBL7495736 | 0.89 | TSHR (0.49) | TSHRLMNANPSR1ATMGAA | |
| SCHEMBL10994841 | 0.88 | ALDH1A1 (0.43) | TSHRLMNANPSR1ATMGAA | |
| SCHEMBL7437024 | 0.85 | LMNA (0.45) | LMNAATMGAAHTTMEN1 | |
| SCHEMBL7435917 | 0.85 | POLB (0.48) | TSHRLMNANPSR1ATMHTT | |
| SCHEMBL7429567 | 0.84 | ALDH1A1 (0.46) | TSHRLMNANPSR1HTTMEN1 | |
| SCHEMBL7440717 | 0.83 | POLB (0.45) | LMNANPSR1GAAHTTMEN1 | |
| SCHEMBL7437941 | 0.83 | TSHR (0.43) | TSHRLMNANPSR1ATMHTT | |
| SCHEMBL7430532 | 0.83 | KMT2A (0.39) | TSHRLMNAATMGAAHTT | |
| SCHEMBL7446182 | 0.82 | CCR2 (0.40) | TSHRLMNANPSR1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |