Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989717 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| SCHEMBL7430532 | 0.84 | KMT2A (0.39) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7428126 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| SCHEMBL7434317 | 0.83 | POLB (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7437126 | 0.82 | MCHR1 (0.35) | MCHR1KMT2ALMNAPOLBTP53 | |
| SCHEMBL7446327 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| SCHEMBL7446165 | 0.81 | TSHR (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL7434220 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7446109 | 0.80 | LMNA (0.49) | ALDH1A1MCHR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7431672 | 0.80 | LMNA (0.53) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |