SCHEMBL743415

SCHEMBL743415

C=CCCC1=CC=CC1=C(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL744432 0.91 ALDH1A1 (0.33) AKT1ALDH1A1
SCHEMBL647169 0.76 PTGS2 (0.38)
SCHEMBL743416 0.67 TDP1 (0.32) AKT1ALDH1A1
SCHEMBL4389892 0.64 AKT1 (0.34) AKT1ALDH1A1
SCHEMBL9226914 0.62 CES1 (0.43) ALDH1A1
SCHEMBL744433 0.61 TLR8 (0.32) AKT1ALDH1A1
SCHEMBL4387095 0.61 L3MBTL1 (0.34) AKT1ALDH1A1
SCHEMBL49747 0.61 ALDH1A1 (0.48) ALDH1A1
Phenol SCHEMBL10569692 0.61 CA12 (0.58) ALDH1A1
SCHEMBL20521131 0.60 MAPT (0.38) AKT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239190-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO LP (US) 2020-01-29 EP disclosed
EP-3239190-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2017-11-01 EP disclosed
EP-1984408-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-07-26 EP disclosed
US-8268944-B2 Dual metallocene catalysts for polymerization of bimodal polymers Chevron Phillips Company, L.P. (US) 2012-09-18 US disclosed
US-20120190804-A1 DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-26 US disclosed
US-8138113-B2 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-03-20 US disclosed
US-20110201770-A1 DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-08-18 US disclosed
US-7960487-B2 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-06-14 US disclosed
US-7732542-B2 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2010-06-08 US disclosed
US-20100069582-A1 POLYMERIZATION CATALYSTS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-03-18 US disclosed
US-7652160-B2 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching Cheveron Phillips Chemical Company, L.P. (US) 2010-01-26 US disclosed
US-7619047-B2 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-11-17 US disclosed
US-20090281342-A1 POLYMERIZATION CATALYSTS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2009-11-12 US disclosed
US-7517939-B2 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-04-14 US disclosed
EP-1989238-A1 DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS Chevron Phillips Chemical Company LP (US) 2008-11-12 EP disclosed
EP-1984408-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2008-10-29 EP disclosed
WO-2007101053-A1 DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-09-07 WO disclosed
US-20070197374-A1 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-08-23 US disclosed
WO-2007092753-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-08-16 WO disclosed
US-20070179044-A1 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281342-A1 POLYMERIZATION CATALYSTS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING PARG, PARP1, PCNA AKT1 3552/4885ALDH1A1 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.