Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438480 | 0.90 | LMNA (0.44) | EPHX2LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL7431389 | 0.90 | HPGD (0.51) | POLBLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7435319 | 0.90 | EPHX1 (0.47) | EPHX2LMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7436670 | 0.88 | NPC1 (0.44) | POLBEPHX2SMN1; SMN2KMT2APRMT5 | |
| SCHEMBL7438375 | 0.88 | DRD3 (0.49) | GAAPOLBEPHX2LMNASMN1; SMN2 | |
| SCHEMBL7438986 | 0.88 | SMN1; SMN2 (0.50) | GAAEPHX2LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7440221 | 0.87 | ALDH1A1 (0.47) | GAALMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7441435 | 0.85 | L3MBTL1 (0.43) | GAALMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7435567 | 0.85 | TEAD1 (0.46) | GAAEPHX2KMT2AHSD11B1PRMT5 | |
| SCHEMBL7439123 | 0.85 | NPC1 (0.50) | GAALMNASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |