SCHEMBL743566

SCHEMBL743566

N#Cc1[c]ccc(C#N)c1C#N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10780755 0.76 TSHR (0.37) PGRAR
SCHEMBL28232147 0.72 CYP2A6 (0.33)
SCHEMBL7299622 0.71 PGR (0.30) PGRAR
SCHEMBL653188 0.71
SCHEMBL328971 0.70 TSHR (0.39)
SCHEMBL744484 0.70
SCHEMBL28063320 0.69 CYP11B1 (0.30)
SCHEMBL28186023 0.69 VCAM1 (0.38)
SCHEMBL152358 0.68 TSHR (0.39) PGRAR
SCHEMBL31399295 0.68 TSHR (0.39) PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825660-A Compound, thermal activation delayed fluorescence material, organic electroluminescent device and application 北京鼎材科技有限公司 2020-10-27 CN claimed
CN-101472924-A KV1.5 potassium channel inhibitors WYETH CORP (US) 2009-07-01 CN claimed
EP-2035420-A2 KV1.5 POTASSIUM CHANNEL INHIBITORS Wyeth a Corporation of the State of Delaware (US) 2009-03-18 EP claimed
US-7402589-B2 Tri-substituted ureas as cytokine inhibitors THE PROCTER & GAMBLE COMPANY (US) 2008-07-22 US claimed
WO-2007149873-A2 KV1.5 POTASSIUM CHANNEL INHIBITORS WYETH (US) 2007-12-27 WO claimed
US-20070299072-A1 KV1.5 POTASSIUM CHANNEL INHIBITORS WYETH (US) 2007-12-27 US claimed
EP-1737830-A1 TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS The Procter and Gamble Company (US) 2007-01-03 EP claimed
EP-1419128-A4 IMPROVED HYDROLYTIC KINETIC RESOLUTION OF EPOXIDES RHODIA PHARMA SOLUTION INC FOR (US) 2006-02-15 EP claimed
WO-2005105757-A1 TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2005-11-10 WO claimed
US-20050245555-A1 Tri-substituted ureas as cytokine inhibitors THE PROCTER & GAMBLE COMPANY (US) 2005-11-03 US claimed
EP-1419128-A1 IMPROVED HYDROLYTIC KINETIC RESOLUTION OF EPOXIDES Rhodia Pharma Solution Inc., (formally Rhodia Chirex Inc.) (US) 2004-05-19 EP claimed
US-6693206-B2 USING COBALT COMPLEX CATALYST RHODIA CHIREX, INC. 2004-02-17 US claimed
US-20030073855-A1 Hydrolytic kinetic resolution of epoxides RHODIA CHIREX, INC. 2003-04-17 US claimed
WO-2003018520-A1 IMPROVED HYDROLYTIC KINETIC RESOLUTION OF EPOXIDES RHODIA PHARMA SOLUTIONS INC. (US) 2003-03-06 WO claimed
WO-2024135508-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
WO-2024038818-A1 FUSED-RING POLYAZAACENE COMPOUND, AND PHOTOELECTRIC CONVERSION ELEMENT OR ORGANIC ELECTRONIC ELEMENT CONTAINING SAME 東ソー株式会社 2024-02-22 WO disclosed
WO-2023167234-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2023-09-07 WO disclosed
EP-0275501-B1 PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS BASF Aktiengesellschaft (DE) 1991-03-06 EP disclosed
US-4857658-A Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0275501-A1 Process for the preparation of (Z)-2-(2-arylethenyl)-arylcarboxylic acids BASF Aktiengesellschaft (DE) 1988-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245555-A1 Tri-substituted ureas as cytokine inhibitors IL1B, IL1A, IL6 PGR 4118/4885AR 4719/4885
US-20070299072-A1 KV1.5 POTASSIUM CHANNEL INHIBITORS KCNA5, KCNH1, KCNK5 PGR 4781/4885AR 2503/4885
US-20030073855-A1 Hydrolytic kinetic resolution of epoxides EPHX2, EPHX1, POR PGR 2755/4885AR 1717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.