Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439752 | 0.88 | MAPT (0.39) | LMNANPC1MAPT | |
| SCHEMBL7428117 | 0.88 | LMNA (0.43) | LMNAMCHR1NPC1FFAR1MTNR1A | |
| SCHEMBL10997095 | 0.86 | FFAR1 (0.38) | LMNAMCHR1NPC1FFAR1MTNR1A | |
| SCHEMBL7431674 | 0.86 | LMNA (0.42) | LMNANPC1CHRM2CHRM1MAPT | |
| SCHEMBL7434853 | 0.84 | MTNR1A (0.40) | LMNAMCHR1KCNH2NPC1FFAR1 | |
| SCHEMBL7434217 | 0.83 | ADRB3 (0.38) | LMNAMCHR1NPC1FFAR1MAPT | |
| SCHEMBL7435694 | 0.82 | ALDH1A1 (0.47) | LMNA | |
| SCHEMBL7446102 | 0.82 | LMNA (0.39) | LMNAMCHR1NPC1FFAR1MTNR1A | |
| SCHEMBL7431667 | 0.82 | LMNA (0.37) | LMNAMCHR1KCNH2NPC1FFAR1 | |
| SCHEMBL7444042 | 0.81 | TSHR (0.39) | MCHR1KCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |