Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428117 | 0.91 | LMNA (0.43) | LMNAMAPTMCHR1FFAR1NPC1 | |
| SCHEMBL7446573 | 0.90 | AIMP2 (0.38) | ADRB3ADRB1LMNAMAPTMCHR1 | |
| SCHEMBL7437776 | 0.89 | LMNA (0.38) | LMNAMAPTMCHR1NPC1 | |
| SCHEMBL10995399 | 0.87 | MAPT (0.40) | LMNAMAPTDRD2DRD3FFAR1 | |
| SCHEMBL7446102 | 0.87 | LMNA (0.39) | LMNAMAPTMCHR1FFAR1NPC1 | |
| SCHEMBL7431674 | 0.85 | LMNA (0.42) | LMNAMAPTNPC1 | |
| SCHEMBL7434853 | 0.85 | MTNR1A (0.40) | LMNAMAPTMCHR1FFAR1NPC1 | |
| SCHEMBL7495730 | 0.84 | CA2 (0.36) | LMNAMAPTMCHR1FFAR1 | |
| SCHEMBL7431667 | 0.84 | LMNA (0.37) | LMNAMAPTMCHR1FFAR1NPC1 | |
| SCHEMBL7435692 | 0.83 | LMNA (0.37) | LMNAMAPTMCHR1FFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |