Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289666 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APKMUSP2 | |
| SCHEMBL7429214 | 0.83 | MEN1 (0.61) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL7434260 | 0.83 | USP2 (0.56) | ALDH1A1MEN1KMT2APKMUSP2 | |
| SCHEMBL7435084 | 0.80 | USP2 (0.76) | ALDH1A1KMT2AUSP2CA1CA2 | |
| SCHEMBL7437444 | 0.78 | KMT2A (0.64) | ALDH1A1MEN1KMT2ATSHRCA1 | |
| SCHEMBL7435728 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL7438908 | 0.78 | POLB (0.50) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL7282808 | 0.76 | PRMT1 (0.62) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL7426498 | 0.76 | ME2 (0.58) | ALDH1A1MEN1KMT2APKMATM | |
| SCHEMBL11601090 | 0.75 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APKMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |