Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292491 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7431609 | 0.82 | NPC1 (0.51) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7429214 | 0.81 | MEN1 (0.61) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7437444 | 0.79 | KMT2A (0.64) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7435890 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7435728 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7426498 | 0.76 | ME2 (0.58) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL7288314 | 0.75 | NPC1 (0.61) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7434820 | 0.75 | ALDH1A1 (0.68) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7439654 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |