Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436013 | 0.84 | LMNA (0.33) | LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL10996527 | 0.82 | BAX (0.30) | — | |
| SCHEMBL7436499 | 0.81 | GNAI3 (0.30) | — | |
| SCHEMBL7430118 | 0.78 | TAAR1 (0.40) | — | |
| SCHEMBL7446833 | 0.77 | MAPT (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL7446273 | 0.77 | HPGD (0.44) | TAS1R3TAS1R1MAPTSMN1; SMN2 | |
| SCHEMBL7435505 | 0.76 | PNMT (0.36) | LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7437379 | 0.76 | MAOA (0.35) | TAS1R3TAS1R1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7446269 | 0.75 | HPGD (0.32) | — | |
| SCHEMBL7436205 | 0.75 | CA2 (0.46) | LMNAMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |