Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431003 | 0.92 | CA2 (0.32) | — | |
| SCHEMBL7437580 | 0.88 | CA2 (0.35) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7437308 | 0.87 | CA2 (0.38) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7433144 | 0.87 | ADRB2 (0.35) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7434496 | 0.83 | LMNA (0.43) | SOS1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7440937 | 0.83 | CA2 (0.38) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7435524 | 0.83 | CA2 (0.38) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7431324 | 0.83 | CA2 (0.38) | ADRB2MLNRADRB1HTR1AADRA2A | |
| SCHEMBL7436853 | 0.82 | MTNR1A (0.43) | KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7446282 | 0.82 | LMNA (0.41) | ADRB2ADRB1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |