Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446282 | 0.96 | LMNA (0.41) | MTNR1ALMNAKDM1AMAOAMAOB | |
| SCHEMBL7440923 | 0.88 | THRA (0.37) | MTNR1AFFAR1SMN1; SMN2KMT2A | |
| SCHEMBL7437308 | 0.86 | CA2 (0.38) | LMNAKDM1AFFAR1SMN1; SMN2KMT2A | |
| SCHEMBL7440201 | 0.84 | ADRB2 (0.38) | MTNR1AFFAR1SMN1; SMN2KMT2A | |
| SCHEMBL7440937 | 0.84 | CA2 (0.38) | FFAR1KMT2A | |
| SCHEMBL7436376 | 0.82 | ADRB2 (0.32) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL7434496 | 0.82 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7433144 | 0.82 | ADRB2 (0.35) | LMNAKDM1ASMN1; SMN2KMT2A | |
| SCHEMBL7437580 | 0.80 | CA2 (0.35) | FFAR1 | |
| SCHEMBL7431324 | 0.80 | CA2 (0.38) | LMNAMAOBFFAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |