Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436853 | 0.96 | MTNR1A (0.43) | LMNAKDM1AMAOAMAOBMTNR1A | |
| SCHEMBL7440201 | 0.88 | ADRB2 (0.38) | MTNR1AADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL7433144 | 0.86 | ADRB2 (0.35) | LMNAKDM1AADRB2ADRB1SMN1; SMN2 | |
| SCHEMBL7440923 | 0.84 | THRA (0.37) | MTNR1AADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL7435524 | 0.84 | CA2 (0.38) | LMNAADRB2ADRB1SMN1; SMN2KMT2A | |
| SCHEMBL7431324 | 0.84 | CA2 (0.38) | LMNAMAOBALDH1A1ADRB2ADRB1 | |
| SCHEMBL7437011 | 0.83 | SLC6A4 (0.35) | LMNAADRB2ADRB1SMN1; SMN2KMT2A | |
| SCHEMBL7436376 | 0.82 | ADRB2 (0.32) | LMNAADRB2ADRB1SMN1; SMN2KMT2A | |
| SCHEMBL7434496 | 0.82 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7437308 | 0.82 | CA2 (0.38) | LMNAKDM1AADRB2ADRB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |