Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444723 | 0.88 | CPA3 (0.38) | TSHRCPA3FOLH1ANPEPALDH1A1 | |
| SCHEMBL7432526 | 0.78 | HSD11B1 (0.46) | TSHRCYP3A4CYP2C19CPA3FOLH1 | |
| SCHEMBL7436715 | 0.78 | SIGMAR1 (0.37) | L3MBTL1GAAACEMEN1KMT2A | |
| SCHEMBL7432640 | 0.76 | ENPP2 (0.47) | L3MBTL1TSHRCYP2C19CYP2D6CPA3 | |
| SCHEMBL7425886 | 0.76 | HSD11B1 (0.44) | TSHRCYP3A4CYP2C19CPA3FOLH1 | |
| SCHEMBL7435805 | 0.74 | CPA3 (0.38) | CPA3FOLH1ANPEPALDH1A1PKM | |
| SCHEMBL7426791 | 0.74 | CPA3 (0.38) | L3MBTL1CPA3FOLH1ANPEPALDH1A1 | |
| SCHEMBL7440464 | 0.74 | FOLH1 (0.41) | CPA3FOLH1ALDH1A1PKMHPGD | |
| SCHEMBL7428787 | 0.73 | KMT2A (0.45) | CYP2C19CYP2D6CPA3FOLH1ALDH1A1 | |
| SCHEMBL7440259 | 0.73 | CPA3 (0.37) | L3MBTL1CPA3FOLH1ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |