SCHEMBL7440259

SCHEMBL7440259

O=C1CN(N(Cc2ccccc2)Cc2ccccc2)C(=O)N1C(CS)Cc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 1/20 0.37
FOLH1 Q04609 1/20 0.37
ALDH1A1 P00352 3/20 0.36
PKM P14618 1/20 0.36
ANPEP P15144 1/20 0.33
MME P08473 3/20 0.32
ACE P12821 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32
ECE1 P42892 1/20 0.32
BLM P54132 1/20 0.32
NPEPPS P55786 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
POLB P06746 1/20 0.32
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435825 0.89 CPA3 (0.39) CPA3FOLH1ALDH1A1PKMANPEP
SCHEMBL7432640 0.77 ENPP2 (0.47) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7435805 0.75 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMANPEP
SCHEMBL7426791 0.75 CPA3 (0.38) CPA3FOLH1ALDH1A1PKMANPEP
SCHEMBL7425886 0.74 HSD11B1 (0.44) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7428787 0.74 KMT2A (0.45) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7436708 0.73 L3MBTL1 (0.39) CPA3FOLH1ALDH1A1PKMANPEP
SCHEMBL7442303 0.73 ALDH1A1 (0.53) CPA3FOLH1ALDH1A1PKMMEN1
SCHEMBL7445692 0.73 ENPP2 (0.36) CPA3FOLH1ALDH1A1PKMMME
SCHEMBL7432526 0.73 HSD11B1 (0.46) CPA3FOLH1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed