Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446102 | 0.91 | LMNA (0.39) | LMNAMCHR1MAPTNPC1MTNR1A | |
| SCHEMBL7434217 | 0.89 | ADRB3 (0.38) | LMNAMCHR1MAPTNPC1 | |
| SCHEMBL7434853 | 0.89 | MTNR1A (0.40) | LMNAMCHR1MAPTNPC1MTNR1A | |
| SCHEMBL7435691 | 0.89 | GAA (0.41) | LMNAMAPTSMN1; SMN2ALDH1A1ADRA1D | |
| SCHEMBL7431667 | 0.88 | LMNA (0.37) | LMNAMCHR1MAPTNPC1MTNR1A | |
| SCHEMBL7428117 | 0.88 | LMNA (0.43) | LMNAMCHR1MAPTNPC1MTNR1A | |
| SCHEMBL10992859 | 0.86 | LMNA (0.38) | LMNAMAPTNPC1MTNR1ASMN1; SMN2 | |
| SCHEMBL7440399 | 0.83 | CA2 (0.38) | LMNAMCHR1MAPTNPC1SMN1; SMN2 | |
| SCHEMBL7431674 | 0.83 | LMNA (0.42) | LMNAMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7437784 | 0.82 | ALDH1A1 (0.43) | LMNAMCHR1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |