Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495736 | 0.92 | TSHR (0.49) | TSHRLMNANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7429340 | 0.90 | POLB (0.49) | TSHRLMNANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7439355 | 0.87 | ALDH1A1 (0.41) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10996565 | 0.87 | TSHR (0.46) | TSHRLMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL7440410 | 0.85 | ALDH1A1 (0.46) | TSHRLMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL7435917 | 0.84 | POLB (0.48) | TSHRLMNANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7447951 | 0.83 | DRD4 (0.50) | TSHRLMNANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7446165 | 0.83 | TSHR (0.43) | TSHRLMNANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7434360 | 0.82 | POLB (0.59) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL7434220 | 0.81 | SMN1; SMN2 (0.48) | TSHRALDH1A1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |