Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993277 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7437941 | 0.87 | TSHR (0.43) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7429340 | 0.87 | POLB (0.49) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL7439350 | 0.82 | USP9X (0.33) | CYP2D6POLB | |
| SCHEMBL7434360 | 0.80 | POLB (0.59) | ALDH1A1KMT2AL3MBTL1TSHRGAA | |
| SCHEMBL7436573 | 0.79 | HTT (0.47) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL7495736 | 0.79 | TSHR (0.49) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7432822 | 0.79 | CA1 (0.49) | ALDH1A1POLBLMNAHTTSMN1; SMN2 | |
| SCHEMBL7441217 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL7436242 | 0.78 | LMNA (0.46) | ALDH1A1KMT2AMEN1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |