Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR3A | P46098 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352703 | 0.86 | DRD2 (0.60) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL2414713 | 0.79 | HTR1A (0.39) | ADRB1HTR1AHTR3ASLC6A2HTR7 | |
| SCHEMBL2209185 | 0.79 | ADRB1 (0.58) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL5785574 | 0.75 | ADRB1 (1.00) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL29446047 | 0.75 | ADRB1 (1.00) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL230424 | 0.75 | ADRB1 (1.00) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL3483188 | 0.75 | DRD2 (0.61) | ADRB1DRD2DRD3HTR1AHTR3A | |
| SCHEMBL8357275 | 0.75 | EPHX2 (0.44) | ADRB1HTR1AHTR3ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL29777392 | 0.73 | ADRB1 (0.96) | ADRB1DRD2DRD3HTR1AHTR3A | |
| Hydrochloric Acid SCHEMBL6577765 | 0.73 | ADRB1 (0.96) | ADRB1DRD2DRD3HTR1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0479665-A2 | 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |