Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482920 | 0.79 | HTR2C (0.38) | HTR1ASLC6A2SLC6A4HTR7HTR2B | |
| SCHEMBL7438142 | 0.79 | ADRB1 (0.59) | HTR1ASLC6A2HTR7ADRB1HTR2B | |
| SCHEMBL2209185 | 0.79 | ADRB1 (0.58) | HTR1AHTR7ADRB1HTR6HTR2B | |
| SCHEMBL8357275 | 0.78 | EPHX2 (0.44) | HTR1ASLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL3483188 | 0.75 | DRD2 (0.61) | HTR1AHTR7ADRB1HTR6HTR2B | |
| SCHEMBL2414711 | 0.73 | ADRB1 (0.62) | HTR1ASLC6A2SLC6A4HTR7ADRB1 | |
| SCHEMBL29448034 | 0.73 | ADRB1 (0.62) | HTR1ASLC6A2SLC6A4HTR7ADRB1 | |
| SCHEMBL234734 | 0.73 | ADRB1 (0.62) | HTR1ASLC6A2SLC6A4HTR7ADRB1 | |
| SCHEMBL739058 | 0.73 | SIGMAR1 (0.52) | HTR1ASLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL6352703 | 0.72 | DRD2 (0.60) | HTR1ASLC6A2SLC6A4ADRB1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150963-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 광주과학기술원 | 2024-07-18 | — | — | WO | disclosed |
| EP-1963288-B1 | SUBSTITUTED OXAZOLE DERIVATIVES WITH AN ANALGESIC ACTION | GRUENENTHAL GMBH (DE) | 2011-09-07 | — | — | EP | disclosed |
| US-7608619-B2 | Substituted oxazole compounds with analgesic activity | GRUENENTHAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| EP-1963288-A1 | SUBSTITUTED OXAZOLE DERIVATIVES WITH AN ANALGESIC ACTION | Grünenthal GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007079928-A1 | SUBSTITUTED OXAZOLE DERIVATIVES WITH AN ANALGESIC ACTION | Grünenthal GmbH (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-1999031096-A1 | PIPERAZINE DERIVATIVES USEFUL AS HYPOGLYCEMIC AGENTS | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0479665-A2 | 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof | TEIKOKU CHEMICAL INDUSTRIES CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | OPRK1, OPRD1, OPRM1 | HTR1A 278/4885SLC6A2 1108/4885SLC6A4 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.