Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292501 | 0.86 | SIGMAR1 (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7431631 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7429214 | 0.79 | MEN1 (0.61) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7288317 | 0.77 | POLB (0.39) | ALDH1A1KDM4EPOLBHSD17B10EGFR | |
| SCHEMBL7445738 | 0.69 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7435890 | 0.68 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1KDM4EALOX15 | |
| SCHEMBL7438908 | 0.67 | POLB (0.50) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7438110 | 0.66 | POLB (0.74) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7279134 | 0.66 | CHRM5 (0.46) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7437444 | 0.66 | KMT2A (0.64) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |