Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299611 | 0.90 | ALDH1A1 (0.54) | MEN1ALDH1A1KMT2ASMN1; SMN2MMP8 | |
| SCHEMBL6754301 | 0.83 | MMP8 (0.50) | TSHRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6754303 | 0.83 | MMP8 (0.50) | TSHRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7436034 | 0.83 | MEN1 (0.48) | MEN1ALDH1A1KMT2ASMN1; SMN2MMP8 | |
| SCHEMBL7290036 | 0.79 | MMP2 (0.52) | MEN1ALDH1A1KMT2AMMP2MMP9 | |
| SCHEMBL7429581 | 0.78 | REN (0.52) | MEN1ALDH1A1KMT2ASMN1; SMN2CTSS | |
| SCHEMBL6753268 | 0.75 | KMT2A (0.55) | MEN1ALDH1A1KMT2ASMN1; SMN2MMP8 | |
| SCHEMBL6753269 | 0.75 | KMT2A (0.55) | MEN1ALDH1A1KMT2ASMN1; SMN2MMP8 | |
| SCHEMBL7408631 | 0.75 | CTSS (0.61) | KMT2AMMP8CYP3A4CYP2C19CTSS | |
| SCHEMBL7404835 | 0.75 | CTSS (0.61) | KMT2AMMP8CYP3A4CYP2C19CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343654-A2 | Diol-containing renin inhibitors | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | claimed |
| EP-0343654-A2 | Diol-containing renin inhibitors | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |