Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CALCA | P06881 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313761 | 0.95 | ESR1 (0.36) | ESR1MEN1GPR119KMT2ACTSS | |
| SCHEMBL7431827 | 0.78 | KMT2A (0.40) | ESR1MEN1GPR119KMT2ACTSS | |
| SCHEMBL7440112 | 0.77 | ESR1 (0.40) | ESR1MEN1GPR119KMT2ADPP4 | |
| SCHEMBL7435316 | 0.77 | GPR119 (0.57) | GPR119IRAK4AREGLN2 | |
| SCHEMBL7548362 | 0.76 | KDM4E (0.41) | ESR1MEN1GPR119KMT2ADPP4 | |
| SCHEMBL7297025 | 0.76 | KMT2A (0.41) | ESR1MEN1GPR119KMT2ACTSS | |
| SCHEMBL7344717 | 0.74 | ITGB3 (0.47) | MEN1GPR119KMT2ACTSSCTSK | |
| SCHEMBL7444913 | 0.73 | ESR1 (0.46) | ESR1MEN1KMT2ACTSSCTSK | |
| SCHEMBL7337863 | 0.72 | KDM4E (0.46) | KMT2ACTSSCTSKDPP4CALCA | |
| SCHEMBL7435155 | 0.71 | CTSS (0.42) | MEN1KMT2ACTSSCTSKDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |